What is harder to metabolize -- wine, liquor or beer?
It's not that it's harder to metabolize alcohol -- there are other non-inebriating substances that are hard to metabolize and some drugs (legal and illegal) can stay in the body for months. It's just that alcohol is absorbed into the blood principally from the small intestine. It accumulates in the blood because its absorption is more rapid than its oxidation and elimination. The more alcohol you drink, the more accumulates in the blood. In short, you do yourself in by overloading the system unnaturally.
-- Dr. Ken Krul